Targeted Alpha-Particle Radiotherapy for Cancer
We are developing a new, proprietary class of personalized alpha-particle radiopharmaceuticals to transform the treatment landscape of radiotherapies for cancer. Our unique theranostic approach provides the ability to diagnose the tumor and then treat it.
Harnessing the Power of Alpha-Particles
Alpha-particles deliver large amounts of radioactive energy very specifically to tumors, irreparably damaging DNA and reliably killing the targeted tumor cells. We believe the use of alpha-particles provides numerous benefits over currently used beta-particle radiotherapies. Alpha-particles generate more energy and travel a shorter distance compared to beta-particles, making them more cytotoxic, while reducing their effects on healthy tissue.
More Powerful Than Approved Beta-Particle Therapy
- Higher atomic mass
- Lethal double-stranded DNA breaks
- Cell death assured – NO resistance
Anti-Tumor Immune Response
- Evidence for anti-tumor response alone or in combination with immunotherapies
Precision Delivery Provides Local Deposition
- Deposit energy over 3-5 cell radii vs beta particles (up to 200 cells)